Psychology homework help
 
Case Conceptualization Process
Case conceptualization refers to the process in which one makes sense of a client’s presenting concerns in the context of a theoretical framework. In other words, it refers to how one explains or understands the pseudo-client’s symptoms, personality characteristics, cognitions, feelings, and behaviors in the light of a particular theory or integration of theories. Such understanding should lead to the formulation of counseling goals and intervention strategies.
At this stage, you will conceptualize the client’s case from 1 theoretical orientation at a time. The content of the conceptualization of the same case will differ according to the various theories depending on the aspect of human experiencing that each theory emphasizes.
In general, however, the case conceptualization process (as with the counseling process itself) starts with an understanding of the client’s presenting concerns (as presented in the case summary) from the perspective of the client.
Use the outline below to assist you in developing your Case Conceptualization according to the theory you choose to discuss.
Client’s Presenting Concerns:
This is derived from your Case Summary.
Case Conceptualization:
Present information used to generate hypothesis regarding the origins of the client’s current problems. Use outside sources and the Jones and Butman textbook to explain the concepts utilized in this section. Below offers an outline of how to discuss these issues.
Psychoanalysis or Object Relations Theory:

  1. Explore      current and early relationships as they relate to issues of attachment and      autonomy. This includes gaining an understanding of how the client      understands the world and his/her relationships with others (e.g., the client’s      mental representations based on internalized objects). Understanding the client’s      internal frame of reference will help the counselor understand the client’s      behaviors.
  2. Describe the      ideas and feelings about self that the client might have developed in the      context of these early relations (internalized objects).
  3. Establish a      relationship between the client’s sense of self and current problems, identify      conflictive patterns that the client may be repeating in current life, and      explore to what extent current experiences trigger the client’s emotional      reactions elicited by past experiences (reliving the trauma).
  4. Uncover      defense mechanisms embedded in the client’s presenting concerns and other      symptoms, and explain how they relate to the client’s current difficulties      and past experiences.
  5. Help the      client become aware of issues described above, and help the client process      and resolve early conflicts.

 
Individual Psychology: 
1. Identify how presenting concerns relate to client’s ability to successfully meet specific life tasks.
2. Explore family constellation to discover experiences that might have led the client to develop his/her specific faulty logic. Describe the content of this faulty logic and the sense of self the client developed in the context of these experiences.
3. Establish a connection between the content of the client’s faulty logic and (1) experiences in the family of origin, (2) problems in current life, and (3) the sense-of-self in relation to the world that the client developed.
4. Identify the underlining purpose of the client’s problematic behavior, and describe how it prevents the client from successfully meeting the life tasks.
Person-Centered: 
1. While exploring the client’s presenting concerns, the counselor will assume that internalized conditions of worth have led the client to disconnect from parts of himself/herself. This disconnect, in turn, has resulted in feelings of incongruency and anxiety, which has impaired his/her internal locus of control as well as thwarted his/her self-actualizing tendency.
2. Examine the discrepancy between the client’s self-concept and ideal self-concept. Since the theory proposes that given the adequate facilitative conditions (empathy, positive regard, and congruence) in the counseling relation, clients will be able to reconnect with themselves and find their own way, the theory does not offer much in terms of a framework to explain the particular issues of each client. This is more a theory of the change process itself than a theory of personality development.
Existential:
1. Identify how presenting concerns (problem behaviors/cognitions) relate to specific givens of existence.
2. Elucidate how these difficulties represent (as mechanisms of defense) or are the consequences of the client’s efforts to avoid facing the normal anxiety generated by specific givens of existence.
3. Describe how these defensive behaviors have led the client to experience of neurotic anxiety and/or neurotic guilt and further problems.
Behavioral/Cognitive/REBT:
1. Relate the presenting concerns to faulty learning, irrational thoughts, and/or faulty cognitions.
2. Identify the client’s irrational thoughts (Ellis) and/or specific faulty cognitions or maladaptive thought patterns (Beck), and illustrate how these lead to the problematic behaviors.
3. Describe the antecedent behaviors and cognitions that trigger the client’s maladaptive behaviors and thoughts (this is called behavioral assessment).
Goal Setting and Interventions:
The information provided in the conceptualization process leads to specific counseling goals. Again, use outside sources to support your discussion of Goals and Interventions.
In the psychodynamic approaches (Object Relations and Individual Psychology), these will likely include:
· Resolving earlier conflicts
· Modifying negative aspects of the self
· Facilitating the development of positive aspects of the self in the context of the therapeutic relation

Essay Exam
The Final Essay Examination will cover the material we have studied in Modules 5 – 8. You will need to choose four of the six essay questions to answer. Each question requires a three to five paragraph (250 – 500 word) response, using the correct vocabulary related to the topic. Your answers need to be supported with information from the textbook or other appropriate sources such as peer-reviewed (professional) journal articles. Do NOT use wikipedia or other encyclopedias, dictionaries or online sources such as Ask.com. Be sure to us APA style citations to show where sources were used in your response. For sources other than the textbook, please list them as references at the end in APA format. For maximum points, make sure your work is written using your own words.
For your final exam submission, please respond to four of the following questions:

  1. You are the commissioner of a state lottery system that sponsors daily and weekly drawings. Lottery tickets have not been selling well over the past few months. Describe at least two ways you could take advantage of people’s use of the availability heuristic to boost sales. Explain why you would judge your tactics to be fair or unfair to your customers.
  2. Imagine you have a friend who just last month adopted a set of siblings, a thirteen-month-old and a four-year-old, from an orphanage in a developing country. The orphanage was not a stimulating environment and the four-year-old can only speak a few words in her native language. The thirteen-month-olddoes not seem to speak words in either her native language or in English. Both children appear physically healthy and have started to adjust quite well, emotionally, but your friend is concerned about their language development. Discuss whether their language development is typical of children their age and theextent to which each child can be expected to learn English fairlywell in the next couple of years.
  3. Latisha’s history teacher asked her why so many German people complied with Hitler’s orders to systematically slaughter millions of innocent Jews and others. Latisha suggested that the atrocities were committed because the Germans had become unusually cruel, sadistic people with abnormal twisted personalities. Use your knowledge of the fundamental attribution error to highlight the weaknesses of Latisha’s reasoning and then propose an alternative explanation.
  4. Abraham Maslow suggested that “a person who is lacking food, love, and self-esteem would most likely hunger for food more strongly than anything else.” Conversely, the novelist Dostoyevski wrote, “without a firm idea of himself and the purpose of his life, man cannot live even if surrounded with bread.” What evidence from the field of psychology might support each statement.
  5. Andy, a high school sophomore, lacks self-discipline, fails to plan ahead, and is excessively anxious. He is quickly frustrated by challenging tasks and frequently becomes overly critical of others. Use the psychoanalytic, humanistic, and social-cognitive perspectives to give three contrasting explanations of Andy’s behavior.
  6. Geraldo, a second-year college student, is so fearful of medical procedures that he has avoided routine dental checkups for over three years. He has recently decided to seek help in overcoming his fear. Compare and contrast (what are the similarities and differences) the methods that would be used by (a) a behavior therapist and (b) a psychoanalytic therapist.

TRANSFORMATION OF NURSING PRACTICE THROUGH LEADERSHIP.

Ch. 15 The Future: Transformation of Nursing Practice through Leadership.
Critical Thinking Questions:
-What is the nursing professional practice model? Describe one type of model.
– Visit YouTube on the internet. Search for “nursing” or “nurses.” What do you find? View one of the selections and critique the image portrayed. Discuss in a team with classmates.
– Consider how the five core competencies might be used as a framework for a professional practice model. Describe your model in a narrative form and graphically on long paper. Post it in the classroom and explain your model.

Your initial discussion thread is due on Day 3 (Thursday) and you have until Day 7 (Monday) to respond to your classmates. Your grade will reflect both the quality of your initial post and the depth of your responses. Refer to the Discussion Forum Grading Rubric under the Settings icon above for guidance on how your discussion will be evaluated.

Connecting the Dots: What is an Effective Program?

In Chapter 10, the text addresses primary, secondary and tertiary prevention programs. What are these levels? Give an example of an effective program in each level. Give a brief description of each program, its intended purpose, and target juvenile population. Why do you think they are effective?

When responding to one of your classmates, address one of the programs with a focus on one of the text’s questions below concerning prevention programs. Select one bullet below and present the positives and the negatives for the issue addressed:

Does every juvenile who has been arrested need treatment? Should all juveniles arrested receive the same treatment services? Why or why not?

Should prevention programs be given to everyone, and if so, where? Should we consider ethnicity, race, education, socio-economic standing?

Are the services worth the taxpayer costs? Consider both financial and social costs.

Should we mandate prevention for school aged children, their parents, or for both? What if the parents refuse to participate?

What role does the state have in addressing pre-criminal, status offenses or delinquent behavior? Should the state have the authority to force parents to participate? What sanctions should the state have to enforce compliance?

Your initial post should be at least 250 words in length. Support your claims with examples from the required material(s) and/or other scholarly resources, and properly cite any references. Respond to at least two of your classmates’ posts by Day 7 and continue to support your arguments with examples from the required material(s) and/or other scholarly resources.

PLEASANT VIEW NURSING HOME ESTIMATES THAT ITS BUILDING WILL LAST

Pleasant View Nursing Home estimates that its building will last another ten years and then it will need to be replaced. The home estimates that the capital cost of a new building in ten years will be $10 million. The home plans to set aside a portion of an endowment fund in government bonds to ensure it has sufficient funds to pay for replacement of the building. If we assume that the yield curve is horizontal, the current interest rate on all Treasury securities is 9 percent, and the type of security used for the building fund is Treasury bonds, then the present value of $10 million discounted back ten years at 9 percent is $4,224,108. Suppose interest rates change from the current 9 percent rate immediately after the nursing home has bought the Treasury bonds. What would be the value of the bonds at the end of ten years under each of the following situations? (For simplicity, assume annual coupons).
a. The home buys $4,224,108 of 9 percent, ten-year maturity bonds; rates fall to 7 percent immediately after the purchase and remain at that level; rates rise to 12 percent.”
b. The home buys $4,224,108 of 9 percent, 40-year maturity bonds; rates fall to 7 percent immediately after the purchase and remain at that level; rates rise to 12 percent.
 Psychology homework help
 Constructivism
 
Prior to engaging in this discussion, please read chapters five and  six in your e-book and review the Instructor Guidance. You will discuss the theory of constructivism and its  relationship to learning.

  • Constructivists suggest that a person’s reality is unique from  others and thus, effects what, how, and how effective knowledge is  acquired. This is suggested to be affected by numerous variables such as  culture, past experiences, and past knowledge.

Consider the following as you discuss:

  • What does logical positivism suggest to us about constructivist-based theories? Do you agree or disagree?
  • How do exogenous constructivism, endogenous constructivism, and dialectical constructivism differ and why does it matter?
  • How does situated cognition (discussed in Week 3) support the suggestions made by constructivism?
  • Discuss a personal experience where you feel constructivism  ideologies explained either the effectiveness of, or the  non-effectiveness of, the learning experience. Would you consider this  learning experience exploratory learning, inquiry learning, or  problem-based learning? Why?
  • What implications in learning effectiveness might exist if construction of individualized knowledge is negated?Individualized Knowledge Construction
    Learning Objectives
    After reading this chapter, you should be able to do the following:
    · Explain the fundamental ideologies of constructivism.
    · Describe social constructivism and this perspective’s views of learning.
    · Compare and contrast situated cognition and the foundational ideas of cognitivism.
    · Explain the premise and variables associated with sociocultural theory.
    · Discuss how problem-based learning supports constructivist-based learning theories.

IDENTIFY WAYS TO IMPLEMENT EVIDENCE-BASED RESEARCH IN NURSING PRACTICE.

1.Merge components of the problem description, solution identification, implementation plan, evaluation plan, and dissemination of findings developed in previous weeks into a cohesive capstone proposal. 2.Demonstrate synthesis and integration of course content to professional practice. 3.Identify ways to implement evidence-based research in nursing practice.

Advanced Biochemistry – Metabolism 45 questions assignment

Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Fundamentals of Biochemistry
Fourth Edition
Chapter 18 Electron Transport and Oxidative Phosphorylation
Donald Voet • Judith G. Voet • Charlotte W. Pratt
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
The Structure of the Mitochondrion A Few Aspects of Communication Between Cytosol and
Mitochondrion Overview of Electron Transport in Mito Membrane
Intro to Some New Players – Co-Enzyme Q, Fe-S proteins and Cytochromes
Organization of Electron Transport Generation of Proton Motive Force by Arrangement of e-
carriers ATP synthesis – ATPase is a machine
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Overview: Oxidative Fuel Metabolism
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Overview: Oxidative Fuel Metabolism
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Overview: Oxidative Fuel Metabolism
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 The Mitochondrion
Key Concepts 18.1 • A highly folded, protein-rich inner membrane separates the
mitochondrial matrix from the outer membrane.
• Transport proteins are required to import reducing
equivalents, ADP, and Pi into the mitochondria.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Animal Mitochondrion
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Mitochondrion Cutaway Diagram
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Mitochondrial Cristae
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Inner Membrane Is Rich In Proteins
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Glycerophosphate Shuttle
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Bovine ATP-ADP Translocator: Ligand Induced Conformational Changes
Bovine heart ATP-ADP translocator PDBid 2C3E
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Bovine ATP-ADP Translocator: Positively Charged Cavity Binds ATP
Bovine heart ATP-ADP translocator PDBid 2C3E
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 The Mitochondrion
Checkpoint 18.1 • Draw a simple diagram of a mitochondrion and idenAfy its
structural features.
• Describe how shuBle systems transport reducing
equivalents into the mitochondria.
• Explain how the free energy of the proton gradient drives
the transport of ATP, ADP, and Pi.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Electron Transport
Key Concepts 18.2 • The free energy of electron transport from NADH to O
2 can
drive the synthesis of approximately 2.5 ATP.
• Electron carriers are arranged in the mitochondrial
membrane so that electrons travel from Complexes I and II
via coenzyme Q to Complex III, and from there via
cytochrome c to Complex IV. • The L-shaped Complex I transfers electrons from NADH to
CoQ via a series of iron–sulfur clusters and translocates four
protons to the intermembrane space.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Electron Transport
Key Concepts 18.2 • Complex II transfers electrons from succinate to the CoQ
pool but does not contribute to the transmembrane proton
gradient.
• Electrons from Complex III are transferred to cytochrome c and two protons are translocated during the operaAon of the Q cycle in Complex III.
• Complex IV accepts electrons from cytochrome c to reduce O
2 to H
2 O and translocates four protons for every two
electrons transferred.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Overview of Electron Transport

air
vectory arrangement of alternating carries the electron and proton or the electron only
air
damp on the other side
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Inhibitors Reveal Electron-Transport Chain Sequence of Events
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Reduction Potentials of ETC Components
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Reduction Potentials of ETC Components
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Mitochondrial Electron-Transport Chain
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Iron-Sulfur Clusters
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Complex I
Complex I from Thermus thermophilus PDBid 3M9S
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Oxidation States of FMN & CoQ
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Oxidation States of FMN & CoQ
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Peripheral Arm of Complex I
Thermus thermophilus PDBid 2FUG
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Redox Active Prosthetic Groups Peripheral Arm of Complex I
Thermus thermophilus PDBid 2FUG
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Complex II
Chicken Complex II PDBid 1YQ3
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-1: Cytochromes are Electron -Transport Heme Proteins
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-1: Cytochromes are Electron -Transport Heme Proteins
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Complex III
Yeast Complex III PDBid 1KYO
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
The Q Cycle
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Stigmatellin Blocks Qo Site
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Cytochrome c
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Complex IV
Bovine heart cytochrome c oxidase homodimer PDBid 1V54
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Redox Centers of Complex IV
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Proposed Reaction Sequence for Complex IV
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Electron Transport
Checkpoint 18.2 • Describe the route followed by electrons from glucose to O
2 .
• Write the net equaAon for electron transfer from NADH to
O 2 .
• Assuming 100% efficiency, calculate the maximum amount of
ATP that could be synthesized as a result.
• For each of the electron-transport complexes, write the
relevant redox half-reacAons.
• PosiAon the four electron-transport complexes on a graph
showing their relaAve reducAon potenAals, and indicate the
path of electron flow.
• How did inhibitors reveal the order of electron transport?
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Oxidative Phosphorylation
Key Concepts 18.3 • The chemiosmoAc theory explains how a proton gradient
links electron transport to ATP synthesis.
• ATP synthase consists of an F1 component that catalyzes
ATP synthesis by a binding change mechanism.
• The F0 component of ATP synthase includes a c-ring whose rotaAon is driven by the dissipaAon of the proton gradient
and drives conformaAonal changes in the F1 component.
• For every two electrons that enter the electron-transport
chain as NADH and reduce one oxygen atom, approximately
2.5 ATP molecules are produced, giving a P/O raAo of 2.5.
• Agents that dissipate the proton gradient can uncouple
electron transport and ATP synthesis.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Coupling of Electron Transport and ATP Synthesis
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-3: Bacterial Electron Transport & Oxidative Phosphorylation
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-3: Bacterial Electron Transport & Oxidative Phosphorylation
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
F1 Components of ATP Synthase Protrude From Mitochondrial Cristae
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
F1 Component of ATP Synthase
Bovine F1-ATP synthase PDBid 1E79
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Model of F1F0-ATPase
F1F0-ATPase PDBids 1JNV, 2A7U, and 1B9U
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Binding Change Mechanism for ATP Synthase
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Inner Sleeve of F1 α3β3 Assembly Interacts with γ-Subunit
F1 α3β3 PDBid 1BMF
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Model of F1F0-ATPase
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
pH-Dependent Conformational Change of c Subunit of F1F0-ATPase
C subunit of E. coli F1F0-ATPase PDBid 1COV
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
ATP-Dependent Rotation of c-Ring From F1F0-ATPase
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
ATP-Dependent Rotation of c-Ring From F1F0-ATPase
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Nonphysiological Electron Donor Yields ATP
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Oxidative Phosphorylation Can Be Uncoupled From Electron Transport
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Oxidative Phosphorylation
Checkpoint 18.3 • Summarize the chemiosmoAc theory.
• Explain why an intact, impermeable mitochondrial membrane
is essenAal for ATP synthesis.
• Describe the overall structure of the F1 and F0 components of
ATP synthase. Which parts move? Which are staAonary? Which
are mostly staAonary but undergo conformaAonal changes?
• Summarize the steps of the binding change mechanism.
• Describe how protons move from the intermembrane space
into the matrix. How is proton translocaAon linked to ATP
synthesis?
• Explain why the P/O raAo for a given substrate is not
necessarily an integer.
• Explain how oxidaAve phosphorylaAon is linked to electron
transport and how the two processes can be uncoupled.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Control of Oxidative Metabolism
Key Concepts 18.4 • The rate of oxidaAve phosphorylaAon is coordinated with
the cell s other oxidaAve pathways.
• Although aerobic metabolism is efficient, it leads to the
producAon of reacAve oxygen species.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-4: Uncoupling in Brown Adipose Tissue Generates Heat
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Coordinated Control of Glycolysis and the Citric Acid Cycle
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Coordinated Control of Glycolysis and the Citric Acid Cycle
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Coordinated Control of Glycolysis and the Citric Acid Cycle
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Box 18-5: Oxygen Deprivation in Heart Attack & Stroke
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Electrostatic Effects in SOD
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Proc Natl Acad Sci U S A. 1991 Jun 1; 88(11): 4870–4873. Mitochondrial respiration in hummingbird flight muscles. R K Suarez, J R Lighton, G S Brown, and O Mathieu-Costello Abstract Respiration rates of muscle mitochondria in flying hummingbirds range from 7 to 10 ml of O2 per cm3 of mitochondria per min, which is about 2 times higher than the range obtained in the locomotory muscles of mammals running at their maximum aerobic capacities (VO2max). Capillary volume density is higher in hummingbird flight muscles than in mammalian skeletal muscles. Mitochondria occupy approximately 35% of fiber volume in hummingbird flight muscles and cluster beneath the sarcolemmal membrane adjacent to capillaries to a greater extent than in mammalian muscles. Measurements of protein content, citrate synthase activity, and respiratory rates in vitro per unit mitochondrial volume reveal no significant differences between hummingbird and mammalian skeletal muscle mitochondria. However, inner membrane surface areas per unit mitochondrial volume [Sv(im,m)] are higher than those in mammalian muscle. We propose that both mitochondrial volume densities and Sv(im,m) are near their maximum theoretical limits in hummingbirds and that higher rates of mitochondrial respiration than those observed in mammals are achieved in vivo as a result of higher capacities for O2 delivery and substrate catabolism.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles Matthew E. Pamenter, Crisostomo R. Gomez, Jeffrey G. Richards, William K. Milsom Published 13 January 2016.DOI: 10.1098/rsbl.2015.0797 /.panel-row-wrapper. “Biology Letters” Mitochondria are central to aerobic energy production and play a key role in neuronal signalling. During anoxia, however, the mitochondria of most vertebrates initiate deleterious cell death cascades. Nonetheless, a handful of vertebrate species, including some freshwater turtles, are remarkably tolerant of low oxygen environments and survive months of anoxia without apparent damage to brain tissue. This tolerance suggests that mitochondria in the brains of such species are adapted to withstand prolonged anoxia, but little is known about potential neuroprotective responses. In this study, we address such mechanisms by comparing mitochondrial function between brain tissues isolated from cold-acclimated red-eared slider turtles (Trachemys scripta elegans) exposed to two weeks of either normoxia or anoxia. We found that brain mitochondria from anoxia -acclimated turtles exhibited a unique phenotype of remodelling relative to normoxic controls, including: (i) decreased citrate synthase and F1FO-ATPase activity but maintained protein content, (ii) markedly reduced aerobic capacity, and (iii) mild uncoupling of the mitochondrial proton gradient. These data suggest that turtle brain mitochondria respond to low oxygen stress with a unique suite of changes tailored towards neuroprotection.
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Chapter 18 Control of Oxidative Metabolism
Checkpoint 18.4 • How do the ATP mass acAon raAo and the IF1 protein
regulate ATP synthesis?
• What control mechanisms link glycolysis, the citric acid
cycle, and oxidaAve phosphorylaAon?
• Describe the advantages and disadvantages of oxygen
-based metabolism.
• How do cells minimize oxidaAve damage?
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Copyright 2016 John Wiley & Sons, Inc. All rights reserved. Reproduction or translation of this work beyond that permitted in section 117 of the 1976 United States Copyright Act without express permission of the copyright owner is unlawful. Request for further information should be addressed to the Permission Department, John Wiley & Sons, Inc. The purchaser may make back-up copies for his/her own use only and not for distribution or resale. The Publishers assumes no responsibility for errors, omissions, or damages caused by the use of these programs or from the use of the information herein.

Resume And Job Interview

1. What are three questions you should ask yourself when you begin your job search?
2. What are the most common mistakes people make in preparing their résumés?
3. What should you know about your prospective employer before the job interview?
4. What should the interviewee try to achieve during a job interview? What should you look for? What red flags should you watch for?
5. What can you do in advance to prepare for the changes during the first year of employment?
6. Create your own SWOT analysis. How would you respond to your personal strengths and weaknesses if you were a prospective employer? How can you enhance your strengths and improve in areas of weakness?
7. Draw a career path for yourself, beginning with the present year and extending to the age of retirement. Be sure to include any “twists and turns” of the path you expect to experience along the way and any barriers you expect to encounter. How will you handle these experiences?
Do an online nationwide search for information about current job prospects in nursing.Compare opportunities in various regions of the country. Why do you think these opportunities are the same or different?
5. Develop a list of questions that you should ask a potential employer. What “homework” will you need to do to prepare for an interview?

LOCATE THE NURSE PRACTICE ACT (OR NURSING LAW) FOR YOUR STATE (NEW YORK), AND INVESTIGATE ONE OF THE FOLLOWING ISSUES: DELEGATION BY THE RN TO THE UNLICENSED ASSISTIVE PERSONNEL, USE OF THE TERM NURSING DIAGNOSIS, PATIENT ABANDONMENT (REFUSAL OF AN ASSIGNMENT), OR REQUIREMENTS FOR CONTINUED LICENSURE (PRACTICE, CONTINUING EDUCATION, OR OTHERS). TELL US WHAT YOUR STATE’S LAW SAYS ON THIS ISSUE AND HOW THIS IMPACTS YOUR PRACTICE

. Although every RN in the United States takes the same licensing exam (NCLEX-RN), each state is charged with the licensing of nurses and the creation of law and rules to govern nursing practice in that state (new york). Locate the Nurse Practice Act (or nursing law) for your state (new york), and investigate one of the following issues: delegation by the RN to the unlicensed assistive personnel, use of the term nursing diagnosis, patient abandonment (refusal of an assignment), or requirements for continued licensure (practice, continuing education, or others). Tell us what your state’s law says on this issue and how this impacts your practice
2. Codes of ethics and standards for professional nursing practice have been developed by some professional nursing organizations. These codes and standards guide us in our practice and our interactions with consumers, other nurses, and other healthcare professions. Select at least one of the ethical standards or one of the standards of practice and tell us how you implement this in your current practice or how you will implement it in your future practice. Which standard is most challenging to you, and why?