research article critique (nursing)
The purpose of this assignment is for the student to learn to examine, analyze, critique, and summarize an original research article. Student is to select an article from a list located in Course Resources. There is a choice of articles from which you must choose ONE to complete this assignment.
Course Outcomes
Through this assignment, the student will demonstrate the ability to meet the following course outcomes:
CO1: Examine the sources of evidence that contribute to professional nursing practice. (PO #7)
CO2: Apply research principles to the interpretation of the content of published research studies. (POs #4 and 8)
CO4: Evaluate published nursing research for credibility and lab significance related to evidence-based practice. (POs #4 and 8)
CO5: Recognize the role of research findings in evidence-based practice. (POs #7 and 8)
Points
The assignment is worth a total of 200 points.
Due Date
You are to submit your paper to the Week 6 Research Article Review Dropbox by Sunday 11:59 p.m. MT at the end of Week 6.
Requirements
Through this assignment, the student will:
1. Critique a peer-reviewed study, and in your own words, describe the research question, sample, design of study, data collection method, findings, and limitations of each. (CO 1, CO2,)
2. Summarize the research article and evaluate the significance to nursing. Do not just quote the author’s words. Paraphrase the information. (CO 4, CO5).
Guidelines to writing the Paper
1. Course Resources lists articles from which you are to select ONE to analyze.
2. Retrieve the full-text version of the article from the library. Read it thoroughly.
- Introduction (one paragraph): The introduction should be interesting and capture the reader’s attention.
- Provide a brief description of the research article to be discussed.
- Discuss the purpose of your paper. The purpose statement of the paper should relate to the research article reviewed and the implications that it has to evidence based nursing practice.
- You will need to summarize and analyze the information from the article in your own words
4. Describe the research question for this study in a paragraph.
- Describe the research in greater detail.
- Include your observations about this question.
- Discuss events or trends that could have affected this question.
- You will need to summarize and analyze the information from the article in your own words
5. Describe the research design of this study, and in your own words discuss the design.
a. Discuss the research design of the study.
b. Discuss the strengths and weaknesses of the type of design and hypothesize why the author utilized the design as opposed to others.
c. You will need to summarize the information from the article in your own words
6. Describe the sample.
a. Briefly describe the sample size used for this study
b. Make a judgment as to whether the sample size was adequate and defend your answer.
c. Describe the number or participants and determine if the number of participants was adequate compared to the research question and the intent of the study.
d. Are these numbers adequate? Discuss gaps in that you identified.
e. You will need to summarize and analyze the information from the article in your own words
7. Describe the data collection method(s)’
a. Who collected the data?
b. What tools were used?
c. What were the ethical considerations addressed and discuss gaps you identified.
d. You will need to summarize and analyze the information from the article in your own words
8. Describe the limitations of the study.
a. Identify the limitations within the study
b. Describe how the limitations could be overcome in subsequent studies
c. Comment on why limitations are important to list and discuss within a study
d. You will need to summarize and analyze the information from the article in your own words
9. Describe the findings reported in the study.
a. Describe the findings reported in the study
b. Discuss whether the findings of the study answered the research question posed within the study
c. Discuss the credibility of the findings
d. If the findings do not support the research question posed within the study, what do you believe is the reason?
e. You will need to summarize and analyze the information from the article in your own words
10. Summary
- Summarize important points from the body of your paper including the key components of the paper.
- Include a statement about the research question and the findings.
- Discuss the probability of implementation into practice. Based on these findings, is the evidence that you found on your topic strong enough to suggest a change in practice, or an idea for practice?
- End with a concluding statement.
11. Citations and References must be included to support the information within each topic area. Refer to the APA manual, Chapter 7, for examples of proper reference format. In-text citations are to be noted for all information contained in your paper that is not your original idea or thought. Ask yourself, “How do I know this?” and then cite the source.
- Reference Page: The Reference Page should start on a new page (insert a page break). All references should be cited within the body of the paperas (Author, year) and the full reference should be included in APA format on the reference page. A url link alone is not an adequate reference. See the APA Guidelines in Course Resources for examples of properly formatted references.
Journal
UncategorizedIdentify what you believe are the top three challenges in setting up a hospital-based committee from a managerial perspective.
UncategorizedSelect either Option A or Option B to respond to and indicate within your post which option you chose.
Option A: Identify what you believe are the top three challenges in setting up a hospital-based committee from a managerial perspective. In a 250- to 300-word post, discuss your rationale and address the following questions:
Why are committees advantageous for health care organizations?
What are some of the steps that you as a manager, could take to overcome these challenges?
How would you address conflict and/or divisiveness within the committee or team?
Option B : Committees have been determined as a necessary component to health care organizations. As a manager, you have been tasked to set up a committee with one of the hospital departments. In doing so, consider the following questions:
How much influence should the committee have in the overall management structure?
How would you maintain authority without adopting an autocratic leadership style?
How would you set up an employee team without violating union and labors laws?
1.Explain what Mucor is and how a patient is likely to become infected with Mucor. Describe the pathophysiologic progression of the infection into pneumonia and at least two medical/nursing interventions that would be helpful in treating the patient.
Nursing Essay HelpNRS-410V Module 4 Mandatory DQ – Chest X-Ray..9 Pathophysiology and Nursing Management of Clients Health – Alterations in Pulmonary and Kidney Function Use the image in “Discussion Question Resource: Chest X-Ray” to answer the following Critical Thinking Questions. Examine the x-ray of a patient diagnosed with pneumonia due to infection with Mucor. Refer to the “Module 4 DQ Chest Xray” resource in order to complete the following questions. Critical Thinking Questions: 1.Explain what Mucor is and how a patient is likely to become infected with Mucor. Describe the pathophysiologic progression of the infection into pneumonia and at least two medical/nursing interventions that would be helpful in treating the patient. 2.Examine the laboratory blood test results and arterial blood gases provided in “Discussion Question Resource: Laboratory Blood Test Results.” What laboratory values are considered abnormal? Explain each abnormality and discuss the probable causes from a pathophysiologic perspective. 3.What medications and medical treatments are likely to be prescribed by the attending physician on this case? List at least three medications and three treatments. Provide rationale for each of the medications and treatments you suggest. ]]>
b. Describe how the limitations could be overcome in subsequent studies
Uncategorizedresearch article critique (nursing)
The purpose of this assignment is for the student to learn to examine, analyze, critique, and summarize an original research article. Student is to select an article from a list located in Course Resources. There is a choice of articles from which you must choose ONE to complete this assignment.
Course Outcomes
Through this assignment, the student will demonstrate the ability to meet the following course outcomes:
CO1: Examine the sources of evidence that contribute to professional nursing practice. (PO #7)
CO2: Apply research principles to the interpretation of the content of published research studies. (POs #4 and 8)
CO4: Evaluate published nursing research for credibility and lab significance related to evidence-based practice. (POs #4 and 8)
CO5: Recognize the role of research findings in evidence-based practice. (POs #7 and 8)
Points
The assignment is worth a total of 200 points.
Due Date
You are to submit your paper to the Week 6 Research Article Review Dropbox by Sunday 11:59 p.m. MT at the end of Week 6.
Requirements
Through this assignment, the student will:
1. Critique a peer-reviewed study, and in your own words, describe the research question, sample, design of study, data collection method, findings, and limitations of each. (CO 1, CO2,)
2. Summarize the research article and evaluate the significance to nursing. Do not just quote the author’s words. Paraphrase the information. (CO 4, CO5).
Guidelines to writing the Paper
1. Course Resources lists articles from which you are to select ONE to analyze.
2. Retrieve the full-text version of the article from the library. Read it thoroughly.
4. Describe the research question for this study in a paragraph.
5. Describe the research design of this study, and in your own words discuss the design.
a. Discuss the research design of the study.
b. Discuss the strengths and weaknesses of the type of design and hypothesize why the author utilized the design as opposed to others.
c. You will need to summarize the information from the article in your own words
6. Describe the sample.
a. Briefly describe the sample size used for this study
b. Make a judgment as to whether the sample size was adequate and defend your answer.
c. Describe the number or participants and determine if the number of participants was adequate compared to the research question and the intent of the study.
d. Are these numbers adequate? Discuss gaps in that you identified.
e. You will need to summarize and analyze the information from the article in your own words
7. Describe the data collection method(s)’
a. Who collected the data?
b. What tools were used?
c. What were the ethical considerations addressed and discuss gaps you identified.
d. You will need to summarize and analyze the information from the article in your own words
8. Describe the limitations of the study.
a. Identify the limitations within the study
b. Describe how the limitations could be overcome in subsequent studies
c. Comment on why limitations are important to list and discuss within a study
d. You will need to summarize and analyze the information from the article in your own words
9. Describe the findings reported in the study.
a. Describe the findings reported in the study
b. Discuss whether the findings of the study answered the research question posed within the study
c. Discuss the credibility of the findings
d. If the findings do not support the research question posed within the study, what do you believe is the reason?
e. You will need to summarize and analyze the information from the article in your own words
10. Summary
11. Citations and References must be included to support the information within each topic area. Refer to the APA manual, Chapter 7, for examples of proper reference format. In-text citations are to be noted for all information contained in your paper that is not your original idea or thought. Ask yourself, “How do I know this?” and then cite the source.
Assessing and Treating Clients with With Bipolar Disorder
Nursing Homeworksplagiarism must be less than 15% . i need the assignment is 11 hours.
Assignment: Assessing and Treating Clients with With Bipolar Disorder
Bipolar disorder is a unique disorder that causes shifts in mood and energy, which results in depression and mania for clients. Proper diagnosis of this disorder is often a challenge for two reasons: 1) clients often present as depressive or manic, but may have both; and 2) many symptoms of bipolar disorder are similar to other disorders. Misdiagnosis is common, making it essential for you to have a deep understanding of the disorder’s pathophysiology. For this Assignment, as you examine the client case study in this week’s Learning Resources, consider how you might assess and treat clients presenting with bipolar disorder.
Learning Objectives
Students will:
The Assignment
Examine Case Study: An Asian American Woman With Bipolar Disorder. You will be asked to make three decisions concerning the medication to prescribe to this client. Be sure to consider factors that might impact the client’s pharmacokinetic and pharmacodynamic processes.
At each decision point stop to complete the following:
you can edit or use my sample with same medication therapy.
Walden University .. 6630n
2 Assessing and Treatment for Bipolar Disorder Patient Introduction Bipolar disorder is not an uncommon illness. It is a very chronic and severe mental disorder, affecting approximately 1-2% of the adult population. The signs and symptoms of bipolar disorder are different depending on the type of episode (i.e., manic or depressive). Each episode marks a critical change from the way a person usually acts and their typical mood, and can be characterized by a sudden change in the general attitude of the patient, the way the patient thinks and the behavior. 1 The changes will be sudden that it will be noticed by people around (Robert et al., 2017). This dangerous demonstrative unpredictability mood disorder can be found in all area of life, that is, from the poor to the rich, this disorder affects millions of people in all facets of life (Robert et al., 2017). Bipolar disorder can be seen mostly in the age starting at 25years or older, but it is not totally absent in the teenage age. It shows that about 2.6 percent of the population are diagnosed as bipolar. 3 (National Alliance on Mental Illness, 2017).
If not well treated ,Bipolar disorder can be critical; 1 early identification of symptoms with an appropriate treatment plan may include psychotherapy, medications, a healthy lifestyle and a regular schedule will keep the patient healthy (National Alliance on Mental Illness. (2017). 1 The NP should have a good understand of this disorder to be able to take care of this the patient because of its long-term management and how it affects the health in totality (National Alliance on Mental Illness. (2017). 1 My focus of this paper will look into an Asian American Woman with a bipolar disorder, symptoms management, diagnosing the symptom, and the complete treatment. The paper will consider the most safe and appropriate options of treatment and the outcome as the treatment, and care.
Decision Selected My patient is an Asian American woman age 39 years with 4 children and 3 ground children. The husband notices that sometimes she will be singing loud to the top of her voice and dancing not to the music she sang. In another time she will just fill like not doing anything and nothing will interest her, and she will lay on the bed for hours without going to the business she spent her years building and love so much.Patient is withdrawn and non-interactive. 4 She is diagnosed Bipolar disorder.
1 Decision # 1 Reason Selected My best treatment of choice for this disorder will be to begin Risperdal 2 mg orally twice a day. Risperdal is the best choice to treat bipolar disorder. (Lee et al., 2011). Risperdal called risperidone is in the chemical class benzisoxazole derivatives which are antipsychotic. It is an effective medication for bipolar disorder (Lee et al., 2011). The reasons of choosing Risperdal is because it is used to treat schizophrenia and the risperidone works with the brain to stabilize the brain (Lee et al., 2011). Risperidone rebalances dopamine and serotonin to improve thinking, mood, and behavior. Risperidone belongs to a class of drugs called atypical antipsychotics approved by U.S. Food and Drug Administration (FDA) The drug is also used to treat symptoms of bipolar disorder and irritability (NAMI, 2017).
Expected Results We will need to have some subjective and objective changes. 1Patient should be able to verbalize changes within the first month of the treatment.
During the next visit with the patient after one month, she is expected to express changes in the clarity of her brain. The freedom from indistinctness or ambiguity because of the medicine will help her to balance certain natural substances in her brain.She should also notice a change in her ability to concentrate on her activities (Lee et al., 2011). No side effects.
Differences between Expected outcome and Actual outcome Patient came back after a month (4 WEEKS) and report that she experiences some improvement in the symptom including some improvement with concentration. My patient reported some drowsiness. 1 Drowsiness is one of the side effect of high dose of Risperdal. The genetic testing, reveals that she is positive for CYP2D6. Asians are more likely to have decreased CYP2D6 activity compared to Caucasians (Lee et al., 2011). I will reduce the dosage of this medication. 1 A positive outcome should be that there was a little bit of improvement in symptoms, patient able to sleep, more concentration. Patient and family report drowsiness during the day time which is one the side effect of high dose Risperdal.
Decision Point Two Reason Selected The next best option is not to discontinue Risperdal, but to lower dose to Risperdal 1 mg orally at hours of sleep (HS) since expected outcome was not achieved based on decision one. My patient and , her family reported that patient has been drowsy during the day because of Risperdal 2mg. I will continue on Risperdal because the patient confirm improvement on the symptoms and the side effect observed was a regular adverse reaction because of her descendant background (American Psychiatric Association, 2017). The reduction to Risperdal 1mg BID to Risperdal 1 mg will be closely monitor.
Expected Results Risperdal 1mg orally at bedtime is a reduced dosage from the 2mg which is expected to eliminate the drowsiness and toxicity in the patient Stahl, (2013).The patient is expected to continue to have decrease in the bipolar symptom. The effect of the medication should be observable and notice by the family member as a testimony (American Psychiatric Association, 2017).
Differences between Expected outcome and Actual outcome During the patient four weeks follow up examination shows that the bipolar disorder symptom dissipated to noticeable level. This indicate a therapeutic effect of Risperdal 1mg at night brought about the therapeutic effect on the patient and patient is tolerating and adjusting to the medication in a positive way (Dean, 2017). The patient did not experience the drowsiness and there was no toxicity, therefore the expected result and the actual result were the same. Risperdal therapy will continue with this medication and the dosage, and a close monitoring will still be needed until the next four weeks appointment (Dean, 2017).
Decision Point Three Decision Selected Risperdal 1mg orally at HS will be continued Reason for Selection The decision to continue with the medication was because the desire result, and the actual result are in pari-passu. To change the current medication or tamper with the dosage may offset the patient and thereby destabilize the rate of her healing (Dean, 2017). The patient is still under assessment and close monitoring continue until the next appointment date.
Expected Results It is expected that the patient will increase in good mental stability and continue to maintain reduction in bipolar disorder symptom with the dosage of Risperdal 1mg at night (Robert et al., 2017). The patient is anticipated to having good sleep at night and well improve in her interaction with relatives and friends, with ability to concentrate on matters that concern her and carrier (Robert et al., 2017).
Differences between Expected outcome and Actual outcome The therapeutic decision is working in this patient in accordance to the expectation. The treatment agrees with the standard way of treatment of an Asian descendant, the starting procedural treatment for bipolar disorder to the maintaining of such patient that are been positive for CYP2D6.The side effect of drowsiness in the day and toxicity is agreement with Asian descent (Robert et al., 2017). The patient will have to be place on the same medication till the next visit for examination. The actual result is that the medication is achieving the therapeutic effect that is needed by the patient (Dean, 2017).
Ethical Considerations for Treatment plan Ethics demand that a patient should agree to treatment before it could be administering unto the patient. The law concerning patient’s preferences for treatment are overlook when the patient is in jeopardy of life threatening or severe psychiatric illness. Psychiatric advance directives are employing to make decision on the patient (Srivastava, 2011). When a practitioner treating a patient with bipolar is confronted with ethical conflicts of helping the patient to attain best result or their autonomy. The autonomy will be the choice of the practitioner (Srivastava, 2011). The law clearly stipulate that practitioners should always carefully consider what moral weight should be given to the values of doing well and avoiding harm (U.S. Food and Drug Administration, 2017).
2 Conclusion Psychiatric nurses should assess the function of the client not only during admission even during remission period and plan for rehabilitation services since functioning is a complex and demanding task. However, it is very important to bring back the client to his fullest possible level to normal life by planning effective psychoeducation about illness, communication training and teaching problem solving skills to client and family. 1 Many drugs are available for the treatment of bipolar disorder, but the professional will have to carefully select a medication that will be the best treatment for the patient. It is worth knowing that genetics influences the absorption of drugs, metabolism, excretion, and distribution. In the case study the Asian woman with positive CYP2D6 will exhibit a certain side effect which will not be in a patient with negative CYP2D6 (Dean, 2017). Therefore, the dosage and frequent of dispensing of drugs be based on the genetic testing (National Alliance on Mental Illness, 2017). The treatment of bipolar disorders in Asian descent must be handled carefully and in accordance with the Food and Drug Administration set guidelines (U.S. Food and Drug Administration, 2017). In conclusion the safety of the patient and the life of family and friends should be the paramount concern of the practitioners.
References American Psychiatric Association. (2017). 1 Treatment of Patients with Bipolar Disorder.
Retrieved from: 1http://psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/bipolar.pdf Dean, L. (2017). 1 Risperidone Therapy and CYP2D6 Genotype. Retrieved from:
1 https://www.ncbi.nlm.nih.gov/books/NBK425795/ Lee, S. Y., Martins, S. S., Keyes, K. M., & Lee, H. B. (2011). 1 Mental Health Service Use by Persons of Asian Ancestry With DSM-IV Mental Disorders in the United States. Psychiatric Services (Washington, D.C.), 62(10), 1180–1186.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698479/ Nami National Alliance on Mental Illness. (2017). 1 What Is Risperdal and What Does It Treat?
Retrieved from: 1 https://www.nami.org/learn-more/treatment/mental-health-medications/risperidone (Risperdal).
Robert, M., Keck, P., & David Solomon, D. (2017). 1 Bipolar disorder in adults:Choosing maintenance treatment. Retrieved from: 1https://www.uptodate.org/contents/bipolar-isorder-in-adults-choosing-maintenance-treatment Srivastava, S. (2011). Ethics Commentary: Bipolar Disorder: 1 Ethical Considerations in the Treatment of Bipolar Disorder. Retrieved from:
1 https://focus.psychiatryonline.org/doi/abs/10.1176/foc.9.4.foc461?journalCode=foc Stahl, S. M. (2013). 1 Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). New York, NY: Cambridge University Press.
U.S. 1 Food and Drug Administration. (2017). 1 The Facts on Bipolar Disorder and FDA- Approved Treatments. Retrieved from: 1https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm530107.htm
Sociology homework help
Uncategorizedreview the media piece How Prohibition Encouraged Women to Drink (Links to an external site.) https://daily.jstor.org/how-prohibition-made-womens-drinking-more-acceptable/?cid=soc_fb_JSTOR (this is the link)
and the journal article, “Bootlegging Mothers and Drinking Daughters: Gender and Prohibition in Butte, Montana”.https://www-jstor-org.proxy-library.ashford.edu/stable/2713337?seq=1#metadata_info_tab_contents (this is the link)
In this last discussion, we address mixed methods, which brings together quantitative and qualitative approaches in unique ways. This discussion will support you in understanding the unique application of mixed methods in research. We will also bring the weeks of discussions together by addressing the value of understanding the human experience in society through research and specifically how research reporting can aid our understanding of social phenomena as well as influence social and public policy.
In your initial post, address the following:
Your initial post should be at least 650 words in length. Support your claims with examples from the required material(s) and/or other scholarly resources, and properly cite any references.
Provide nursing care to patients and their families in critical and emergent care settings based on theories and principles of nursing and related disciplines.
Nursing HomeworksTHIS PURPOSE OF THIS ASSIGNMENT IS FOR THE STUDENT TO PRESENT A COMPLETE PICTURE OF NURSING CARE OF…
This purpose of this assignment is for the student to present a complete picture of nursing care of a critically-ill
individual encountered during the course. The student will demonstrate clinical reasoning skills and will discuss
interdisciplinary care that had been incorporated and/or anticipated during the care of the critically-ill individual.
COURSE OUTCOMES
This assignment enables the student to meet the following course outcomes:
CO 1: Provide nursing care to patients and their families in critical and emergent care settings based on theories and
principles of nursing and related disciplines.
CO 2: Initiate the use of appropriate resources in direct care responsibilities within critical-care and emergent care
settings.
CO 3: Demonstrate effective therapeutic communication and relationship skills in providing care to patients and
families in critical-care and emergent care settings.
CO 4: Demonstrate effective clinical decision-making based on critical thinking skills and legal, ethical and
professional standards and principles when caring for patients and families in critical care and emergent care
settings.
CO 5: Implement a plan of for continued personal, professional, and educational development related to nursing
practice within critical-care and emergent care settings.
CO 7: Use evidence including research findings from nursing and related disciplines to answer clinical questions
related to nursing care of patients in critical care and emergent care settings
Accounting homework help
UncategorizedLego Project Instructions
Fall 2020
Due Date: 11/16/20
The Lego Project will be due Nov 16th at 11:59PM
The purpose of this project is for you to reinforce the fundamentals of managerial accounting presented in ACCT 2102. You can do this in groups of two. On the coversheet on your written deliverable please include both names if you worked in a group. In addition, your cover sheet should contain the name of your creation and a picture of your creation. Please include both names on the PowerPoint as well.
You will be creating a Lego kit either by drawing or a Lego building website. The number of Legos per creation will differ for each group depending on the creation. You must use a minimum of 100 pieces to create your Lego creation. This project should not cost you any money you should be able to download the software off of Lego.com or draw your creation. If you find another website similar, you are free to be creative. If you have Legos, you may also build an actual structure.
Assume you are creating a Lego kit to resell. Also, assume that you are presenting this project to the Executive Vice President of Product and Marketing Development.
Grading: 20% actual creation 40% two-page written deliverable 40% presentation
Actual Creation 20 points
Written Deliverable 40 points
Presentation (PowerPoint and Presentation) 40 Points
Total Points 100 Points
Your deliverable and presentation will be judged on both creativity and the informational content of the report. DO NOT SUBMIT A DELIVERABLE THAT RESEMEBLES JUST ANSWERING THE QUESTION IN ORDER OR THAT RESEMBLES A RESEARCH PAPER.
Direct Materials Cost:
Bricking Listing- Use this listing of Lego pieces to determine your material cost. Your only material used should be Lego pieces. Assume the following costs for the Lego bricks in determining the cost of your creation:
Lego Plates: 5 cents each
Lego Bricks: 8 cents each
Lego Special Pieces: 10 cents each (if the piece is not a plate or a normal Lego brick, it should be classified as a special price- any size or shape)
Direct Labor Cost: Direct labor cost are recorded at 25% of your total direct materials cost.
Manufacturing Overhead Cost: Manufacturing overhead costs are recorded at 30% of your direct labor cost.
Required: You should create a two-page maximum information sheet about the creation you build. The written deliverable should contain at a minimum the information listed below. However, it can not exceed two pages, thus you must also think about creativity when preparing your deliverable. You will also create a PowerPoint containing the following information and include a voice over power point in place of a presentation.
Remember you are trying to sell your project to the Executive Vice President of Product and Marketing Development; thus, you want to use creativity when presenting this information.
· A unique name for your creation along with the selling price of your Lego Kit. Make sure you use creativity in choosing the name of your creation. Comment on the reasonableness of the selling price of your creation and how you calculated the selling price.
· A discussion of the types of costs associated with manufacturing the Legos for your creation. This does not include the dollar amount of cost, just the TYPES of costs. Think through the manufacturing process and include all of the types of costs that you can identify that would be used in this manufacturing process. (Think about obvious types of items used in any manufacturing process.) You might draw a flowchart depicting the manufacturing process and comment on types of costs or use another interesting approach for presenting the information. Diagram in as much detail as you can, the manufacturing process of your Lego creation.
· Summarize all costs of production in a Production Cost Sheet format. One possible format is shown below (feel free to add any parts to the list that you might need- customize the list to your creation):
PLATES LISTED BY SIZE
QUANITITY USED
COST/UNIT
TOTAL COST
1X1
2X2
2X3
2X4
2X6
2X8
2X10
4X4
4X6
4X10
# OF UNIQUE PLATES USED
SUBTOTAL (A)
BRICKS LISTED BY SIZE
QUANTITY USED
COST/UNIT
TOTAL COST
1X1
1X2
1X3
1X4
1X8
2X2
2X4
2X6
2X8
2X10
# OF UNIQUE BRICKS USED
SUBTOTAL (B)
SPECIAL PARTS- LIST BY DESCRIPTION
QUANTITY USED
COST/UNIT
TOTAL COST
# OF UNIQUE SPECIAL PARTS
SUBTOTAL (C)
TOTAL MATERIALS COST (A) + (B) + (C)
Labor Cost
25% of total direct materials cost
Overhead Cost
30% of direct labor cost
Total Cost
Plus markup (You must choose your markup percentage)
Total Selling Price
· Include in your written deliverable and presentation at least two pictures. One picture should be a picture of your kit “in process.” The second picture should be a picture of the actual creation. Your deliverable will be strengthened if you present several pictures (preferably in various stages).
· Identify and explain (with references to your particular project) five concepts covered in class or in your book which would help when producing and costing your creation. Do not use project cost (DM, DL, or MOH) as part of this question. These types of costs are covered above.
· Currently, there is a discussion about the effect of plastics on the future of our planet. Include a section in your presentation and deliverable that discusses whether or not it is possible to offer sustainable Lego products. Provide a list of any resource that you use in answering this question.
attachment
LegoProjectFall2020.docx
attachment
LegoProjectEXAMPLE1.docx
Substantive Initial
UncategorizedIt is anticipated that the initial discussion response should be in the range of 250-300 words. Response posts must demonstrate topic knowledge and scholarly engagement with peers. This is not the only criteria utilized for evaluation; substantive content is imperative. All questions in the topic must be addressed. Please proofread your response carefully for grammar and spelling. Do not upload any attachments. All responses need to be supported by a minimum of one scholarly resource. Journals and websites must be cited appropriately. Citation and reference must adhere to APA format (6th Ed.)
Select ONE of the questions listed below and create a substantive initial post. Please post the question number you chose in the title of your post. (i.e. Question 2 Postpartum check)
Human Anatomy and Physiology
Nursing HomeworksNATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE
by James A. Hewlett Science and Technology Department Finger Lakes Community College
Bad Fish: Human Anatomy and Physiology Edition
Part I – Poisoned! One evening during a recent trip to Indonesia, Dr. Marshall Westwood from the Montana Technical Institute sat down to a meal of puff erfi sh and rice. Within an hour of returning to his hotel room, Dr. Westwood felt numbness in his lips and tongue, which quickly spread to his face and neck. Before he could call the front desk, he began to feel pains in his stomach and throat, which produced feelings of nausea and eventually severe vomiting.
Fearing that he had eaten some “bad fi sh” for dinner, Dr. Westwood called a local hospital to describe his condition. Th e numbness in his lips and face made it almost impossible for him to communicate, but the hospital staff managed to at least understand the address he gave them and they sent an ambulance in response. As Dr. Westwood was rushed to the hospital, his breathing became increasingly diffi cult.
Doctor’s Notes Th e patient presented in the ED with severe headache, diaphoresis, motor dysfunction, paresthesias, nausea, and an ascending paralysis that spread to the upper body, arms, face, and head. Th e patient was cyanotic and was hypoventilating. Within 30 minutes of presenting in the ED, Dr. Westwood developed bradycardia with a BP of 90/50. Atropine was administered in response to the bradycardia. IV hydration, gastric lavage, and activated charcoal followed a presumptive diagnosis of tetrodotoxin poisoning based on the clinical presentation in the ED. Five hours after intervention, the following vitals were noted:
• BP 125/79 • HR 78bpm • Oxygen saturation: 97% on room air
Follow-up Within a few hours, Dr. Westwood’s condition improved and he was on his way to a full recovery. After discussing his case with his physician, he learned that he had probably been the victim of a puff erfi sh poisoning. Th e active toxin in the tissues of this fi sh is a chemical called tetrodotoxin. Tetrodotoxin is in a class of chemicals known as neurotoxins due to the fact that it has its eff ects on nerve cells (neurons). Specifi cally, tetrodotoxin blocks voltage-gated sodium ion channels on neurons.
Questions 1. Present the “Doctor’s Notes” portion of the case with a description of the following terms or concepts:
• diaphoresis • motor dysfunction
Page 2“Bad Fish: Human Anatomy and Physiology Edition” by James A. Hewlett
• paresthesias • cyanotic • hypoventilating • bradycardia • gastric lavage • oxygen saturation
2. How many diff erent elements are contained in a molecule of tetrodotoxin? What are the names of these elements?
3. What type of chemical bonds are found in this molecule? Describe the structure of those bonds. 4. As mentioned in the case description, tetrodotoxin is a molecule that blocks voltage-gated sodium ion channels.
Describe the structure of a sodium ion. 5. What is a voltage-gated sodium ion channel? What is it made of? What is its function? 6. Why do sodium ions need channels in order to move into and out of cells? 7. Describe the process involved in the movement of ions through these channels. 8. When nerve cells are at rest, there is an unequal amount of positive and negative charges on either side of a
nerve cell membrane. Th is charge diff erence is called an electrical potential. Describe this “potential” when the neuron is at rest (resting potential).
9. What is happening to the electrical potential of a neuron when it generates an action potential? What is the function of the action potential in neurons?
10. Describe the role of sodium ions and sodium channels in the action potential. 11. What would happen to a neuron if it were exposed to tetrodotoxin? Be specifi c regarding its eff ect on the ability
of a neuron to communicate. 12. Now that you have addressed some of the basic biology of this case, explain why Dr. Westwood experienced
numbness after eating the puff erfi sh meal. 13. Paralysis is a term used to describe the loss of function of muscle. If tetrodotoxin’s eff ect is on neurons, why did
Dr. Westwood experience paralysis? 14. Explain how tetrodotoxin is involved in the development of hypotension and hypoventilation. 15. Briefl y describe the role of the autonomic nervous system in human physiology. What are the two divisions of
this system? 16. Atropine was administered in the ED as part of Dr. Westwood’s care. What eff ect did it have on his vitals after
it was administered? Atropine acts as an antagonist within the central nervous system, which means it acts as a blocker of specifi c cellular functions. What part of the autonomic nervous system does atropine block to produce its eff ect on Dr. Westwood?
Page 3“Bad Fish: Human Anatomy and Physiology Edition” by James A. Hewlett
Part II – Oh No! Not Again After recovering from his TTX poisoning, Dr. Marshall Westwood decided to take a vacation. An avid birder, he decided to go to Papua New Guinea with Bill Whitlatch, an ornithologist friend of his from Montana Technical Institute.
Th ree days into their trip, Bill netted bird with an orange body and black wings and head for closer study. Dr Westwood was very curious and asked Bill if he could have a closer look at the bird. After handling the bird and then later wiping his mouth with his hand, Dr. Westwood noticed that his fi ngers and lips were going numb. His mind immediately fl ashed back to the disastrous trip to Indonesia and he began to panic. Luckily, the symptoms faded before they progressed into anything more serious.
His friend Bill used a key to identify the animal as a pitohui. Th e pitohui are small, social songbirds that live in Papua New Guinea. Th ey are generally about 23 centimeters long with strong legs and a powerful beak. Th eir encounter was the fi rst time anyone had scientifi cally realized the birds’ toxicity.
Before releasing the bird, Dr. Westwood collected feather and tissue samples to bring back to the lab. After returning to Montana, he set out to isolate the toxic compound that he believed was being produced by the pitohui. It appeared that the active ingredient was a homobatrachotoxin. Homobatrachotoxin is a steroidal alkaloid that is similar to batrachotoxin, the toxic principle of the Central American poison arrow frog Phyllobates aurotaenia. Batrachotoxin and homobatrachotoxin are both known to act on the voltage-sensitive sodium channels in excitable tissues.
You and your colleagues received a call from Dr. Westwood asking if you could help elucidate the mechanism of action of this toxic compound. One of the hypotheses is that this toxin acts similarly to TTX.
Questions 17. In your fi rst experiment, you generated action potentials in axons of large neurons obtained from squid in the
presence of this new toxin. You found that after depolarizing, the membrane potential remained positive for an extended length of time, and the repolarization was often extremely delayed. Draw a graph (membrane potential in mV vs. time) to illustrate this eff ect.
18. As you continued to experiment with higher concentrations of the toxin, you found cases when the cell could not repolarize at all, or if it began to repolarize, it would immediately depolarize again. Using this description and the description in the previous question, describe how this toxin acts on voltage-gated sodium ion channels.
Page 4“Bad Fish: Human Anatomy and Physiology Edition” by James A. Hewlett
Image credits: Photograph on page 1, Arothron meleagris, © John E. Randall. Used with permission. Photograph on page 3, Hooded Pitohui, Jack Dumbacher. Courtesy of the Smithsonian National Museum of Natural History.
Case copyright held by the National Center for Case Study Teaching in Science, University at Buff alo, State University of New York. Originally published April 13, 2003. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work.
Part III – Pharmacology In this section, you (or your group) will become a small pharmaceutical company that is trying to develop a drug that can be used in the ED to treat tetrodotoxin poisoning. Th ere is no antidote to tetrodotoxin poisoning. Th erefore, it is extremely important that your company is successful in this endeavor. In your report, you need to include the following:
• Your Company Name: o What do you want to call your company? Be creative!
• Name of Your Drug: • Treatment of:
o What does your drug treat? o What other diseases, problems etc. might it be useful for?
• Mechanism of Action: o Describe how your drug will work. o Be sure to provide details regarding its action. You are now familiar with the activity of this toxin at the
level of molecules and cells, so your description should contain details of how your drug works at that level.
• Dosage Form: o How will it be administered to patients?
• Side Eff ects: o What type of side eff ects might your drug have?
Some of your information will come from your understanding of what tetrodotoxin does to neurons. Th ere is no right or wrong answer to how your drug will work because there currently is no drug to treat this problem.
After you decide how your drug might work, you should consider if its mechanism would lead to side eff ects. In addition, your drug may be useful for other problems related to nerve function. You may want to do some research on drugs that have actions at neurons (specifi cally sodium ion channels) and diseases that involve sodium ion channels. Th is will help you develop your drug.