Respond by offering additional thoughts regarding the examples shared, Systems Development Life Cycle SDLC-related issues, and ideas on how the inclusion of nurses might have impacted the example described by your colleagues.
Initial Post
Consequences of a Healthcare Organization not Involving Nurses
Nurses are the backbone of healthcare and when they are not involved in the design and decision-making processes of the Systems Development Life Cycle the results can be catastrophic. According to the authors Powell-Cope & Nelson (2008), nurses are the frontline and chief users of electronic health record (EHR) systems, it only makes sense they’d have a major say in EHR design and upgrades. Unfortunately, however, in many facilities, EHR design is left primarily to IT and only minor input is taken into consideration from the nursing staff. When subject matter experts, such as nurses, don’t have autonomy and responsibility within the design process, implementing and utilizing an EHR can take longer because providers are distanced from the outcomes (Powell-Cope & Nelson, 2008).
Inclusion of Nurses in EHR Design
When nurses are included in technology design, it enables and enhances safety (Hamer & Cipriano, 2013). A study was done in 2009 on early nursing involvement during the implementation of a Bar Code Medication Administration (BCMA) system. The authors of this study describe how nurses participated in the early design, planning, implementation, and evaluation phases of the BCMA. The study found that the benefits of early nursing involvement in each phase of BCMA technology greatly outweigh the problems that can arise from early nursing involvement (Weckman & Jansen, 2009). This study found that in order to find success when implementing new technologies, it is essential that nurses be involved throughout all phases of the process. Comments and feedback from nurses provide the necessary clues that are needed to resolve underlying systemic issues and can offer possible resolutions.
My Personal Input
My current healthcare facility is changing its EHR system to Epic. They have selected a specific team of nurses and nurse informaticists that are currently part of their healthcare team, to design and adapt the Epic program to meet the institution’s requirements. My facility has named their adaptation of the Epic EHR to Elle. The entire healthcare team has been invited to monthly townhouse meetings which involve disclosing the most recent updates made to Elle and team members are also encouraged to provide input on any modifications they would like to add to Elle. As critical nurses, we are excited that we will finally have a charting system that downloads our vital signs electronically. Before Elle, we had to write our vital signs every 15 minutes on each of our two patients. It might not seem like a big deal, but writing vital signs for two patients can take up a considerable amount of time, especially when a patient is unstable and on multiple drips. If nurses were not involved in the EHR design, downloading vital signs might be something that was overlooked again.
Science homework help
UncategorizedPossible topics areas:
1) Gravitational wave detection and future capabilities – LIGO-LISA-BBO
2) The X Ray universe – what do we learn
3) Future ground and space based telescopes – science enabled and technology required
4) The direct imaging of blackholes via their “event horizon” – such as the EHT – Event Horizon Telescope
5) Adaptive Optics (AO) for optical and IR telescopes – how does it work and how well does it perform
6) Using the Moon as an astronomical observatory – opportunities and challenges
7) Multiple universe theories – can we detect parallel and past universes?
8) The fate of our universe
9) Current “tension” in cosmological data and theories – opportunities for new discoveries
10) The matter-antimatter asymmetry problem in our universe
11) Ideas of unifying gravity and quantum mechanics – “The Theory of Everything”
12) Is time travel possible within the current known theories of Physics – Wormholes
13) Is faster than light travel possible and what are the implications?
14) The radio universe – how does it complement optical surveys
15) The infrared universe – how does it complement optical surveys
16) Upcoming large scale sky surveys such as the LSST program – what can we learn
Introduction to Biochemistry
Nursing HomeworksIntroduction to Biochemistry
4LMS0001
Interpretative assignment 2017-18
Your answers should be written in a Word document. This should only contain the text of the answers (and not the details of the experiments or the text of the questions). The maximum word count for the assignment is 1000 words. The work should be submitted electronically via StudyNet.
Objectives
· To introduce you to data interpretation and develop your interpretive skills.
· To show how metabolism can be studied.
· To show how studies of metabolism can be used to identify biochemical lesions.
· To develop your understanding of the glycolytic pathway.
Learning Outcomes
At the end of this exercise you should be able to:
· Understand what is meant by a U-14C label and how it can be used.
· Be very familiar with the glycolytic pathway.
· Understand some of the principles of the activation and action of toxicants.
· Have developed your ability to analyse data and think about metabolism logically.
Introduction
The glycoside beta drummin has been shown to be an effective reversible male anti-fertility agent in ram and boar. The primary contraceptive effect appears to be directly on spermatozoa within the cauda epididymis.
Adverse side effects have precluded human trials and it was decided to investigate the mechanism of action of beta drummin in order to develop less toxic anti-fertility analogues.
Radiolabelled substrates were used to elucidate where the compound was having an effect on metabolism. The substrates are designated U-14C which indicates that a proportion of the C atoms are the 14C isotope, U indicating that all the carbon atoms in the molecule are labelled rather than one specifically. The following experiments were carried out.
Experiment 1
Ram spermatozoa were washed in buffer (ram spermatozoa washed, RSW) and incubated for 3 hours with U-14C glucose (15mM) or U-14C fructose (10mM) in the presence of beta drummin (0.1mM). Oxygen uptake, as an indicator of aerobic respiration, was measured. Radioactivity recovered in the CO2 released as a result of oxidation of the substrate was also measured. Both were decreased to 50% in treated samples compared with control values. There was no accumulation of lactate.
Experiment 2
Incubation of RSW with U-14C pyruvate (5mM) or U-14C lactate (5mM) needed beta drummin at a concentration of 10-100mM to cause a 50% inhibition in oxygen uptake and 50% inhibition in CO2 released.
Experiment 3
Further incubations of RSW with inhibitor only, such that endogenous substrates (presumably lipid) are required for oxidation, resulted in negligible inhibition. Even when 100mM beta drummin was added the oxygen consumption was decreased by only 20%.
Experiment 4
RSW were incubated with fructose (15mM) in the presence and absence of beta drummin (3mM) and concentrations of glycolytic intermediates were measured. The results for samples treated with beta drummin, expressed as a percentage of control, are shown in Table 1.
Table 1: Concentrations of Intermediates of Glycolysis following incubation of RSW with beta drummin.
* The assay method used could not detect these compounds in control or test incubates. In a separate experiment it was found that if two control incubates were pooled and the pooled volumes reduced by 50%, the assay method could just measure these compounds.
Experiment 5
Purified glycolytic enzymes were prepared from RSW and assayed for activity. Addition of beta drummin at final concentrations as high as 300mM to the reaction cuvettes had no effect on the activity of any of the glycolytic enzymes assayed including hexokinase, phosphofructokinase (PFK), aldolase, triose phosphate isomerise, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, pyruvate kinase and lactate dehydrogenase (LDH).
Questions
1. In just a few sentences explain how the 14C in the labelled glucose and fructose is incorporated into the CO2 released. (Only an overview, precise details of the pathways are not required.)
(10 marks)
2. What is the significance of the lack of accumulation of lactate in Experiment 1?
(10 marks)
3. What two explanations can you offer for the decrease in O2 uptake and CO2 output in the presence of beta drummin?
(10 marks)
4. Explain why the results of Experiment 2 point to some blockage of the glycolytic pathway by beta drummin.
(10 marks)
5. Explain why the results of Experiment 3 confirm the findings of Experiment 2.
(10 marks)
6. Suggest the probable site of beta drummin inhibition from the data in Table 1, explaining your reasoning.
(10 marks)
7. Give reasons why fructose-1,6 bisphosphate should be relatively so high.
(10 marks)
8. Postulate why beta drummin is effective as an inhibitor only when added to crude extracts but not when added to purified enzymes.
(10 marks)
9. What is the probable mechanism of inhibition shown when beta drummin acts in vivo?
(10 marks)
10. What is the physiological explanation for the anti-fertility effect of beta drummin?
(10 marks)
Guidelines
1) The total word count for the document is 1000 words.
2) The assignment should be typed, single-sided, double spaced in size 12 font. Please leave a standard margin on all edges (approximately 2.5 cm) and number the pages.
3) To facilitate anonymous marking please ensure your student number and word count are included in the header/footer of the assignment.
4) You should submit a document that has only the answers to each question (do not include the questions themselves).
5) You should submit a file that has only your student number as the filename.
6) Your name should not appear anywhere in the document.
7) Read through the information given and the questions at least twice before attempting your answers.
Failure to follow these guidelines will result in 5% being deducted from your overall mark.
The information is presented in a logical step-by-step way. Only consider the data for the specific experiment in each question, building on what you have already discovered, without including assumptions from later experiments.
Economics homework help
UncategorizedAlso, provide a graduate-level response to each of the following questions:
Respond to the post of at least two peers, using 100 words minimum each.
[Your initial post should be based upon the assigned reading for the week, so the textbook should be a source listed in your reference section and cited within the body of the text. Other sources are not required but feel free to use them if they aid in your discussion].
[Your initial post should be at least 450+ words and in APA format (including Times New Roman with font size 12 and double spaced). Post the actual body of your paper in the discussion thread then attach a Word version of the paper for APA review].
[Your posts must be substantive and demonstrate insight gained from the course material. A peer response such as “I agree with her,” or “I liked what he said about that” is not considered substantive and will not be counted for course credit. A blank post just to review other submissions will not be tolerated].
Management homework help
UncategorizedIf you consider this small Polish-US Joint venture as a kind of large “multicultural team”, and you were a Polish worker in it, would you say it is achieving its individual-level social process outcomes? (1 mark) Why/why not?(2 marks) [TOTAL: 3 marks]
Requirements
1. Double-spaced, 12ptfont (Times New Roman)
2. 1 page long
Rubric:
a) How well did the response actually answer the question in a logical, clear and comprehensive manner?
b) How well did the response deal with all aspects of the question?
c) How well did the response link the relevant course material?
d) Did the response demonstrate an appropriate effort/level of analysis? To what extent did the response demonstrate original thought or new insights to the issue that falls outside the course materials?
Nursing homework help
UncategorizedAssignment: Evidence-Based Capstone Project, Part 6: Disseminating Results
The dissemination of EBP results serves multiple important roles. Sharing results makes the case for your decisions. It also adds to the body of knowledge, which creates opportunities for future practitioners. By presenting results, you also become an advocate for EBP, creating a culture within your organization or beyond that informs, educates, and promotes the effective use of EBP.
To Prepare:
To Complete:
Create a 5-minute, 5- to 6-slide narrated PowerPoint presentation of your Evidence-Based Project.
Assignment grading rubric
https://class.waldenu.edu/webapps/bbgs-deep-links-BBLEARN/app/course/rubric?course_id=_16742105_1&rubric_id=_1942267_1
Systems Development Life Cycle {SDLC}
UncategorizedRespond by offering additional thoughts regarding the examples shared, Systems Development Life Cycle SDLC-related issues, and ideas on how the inclusion of nurses might have impacted the example described by your colleagues.
Initial Post
Consequences of a Healthcare Organization not Involving Nurses
Nurses are the backbone of healthcare and when they are not involved in the design and decision-making processes of the Systems Development Life Cycle the results can be catastrophic. According to the authors Powell-Cope & Nelson (2008), nurses are the frontline and chief users of electronic health record (EHR) systems, it only makes sense they’d have a major say in EHR design and upgrades. Unfortunately, however, in many facilities, EHR design is left primarily to IT and only minor input is taken into consideration from the nursing staff. When subject matter experts, such as nurses, don’t have autonomy and responsibility within the design process, implementing and utilizing an EHR can take longer because providers are distanced from the outcomes (Powell-Cope & Nelson, 2008).
Inclusion of Nurses in EHR Design
When nurses are included in technology design, it enables and enhances safety (Hamer & Cipriano, 2013). A study was done in 2009 on early nursing involvement during the implementation of a Bar Code Medication Administration (BCMA) system. The authors of this study describe how nurses participated in the early design, planning, implementation, and evaluation phases of the BCMA. The study found that the benefits of early nursing involvement in each phase of BCMA technology greatly outweigh the problems that can arise from early nursing involvement (Weckman & Jansen, 2009). This study found that in order to find success when implementing new technologies, it is essential that nurses be involved throughout all phases of the process. Comments and feedback from nurses provide the necessary clues that are needed to resolve underlying systemic issues and can offer possible resolutions.
My Personal Input
My current healthcare facility is changing its EHR system to Epic. They have selected a specific team of nurses and nurse informaticists that are currently part of their healthcare team, to design and adapt the Epic program to meet the institution’s requirements. My facility has named their adaptation of the Epic EHR to Elle. The entire healthcare team has been invited to monthly townhouse meetings which involve disclosing the most recent updates made to Elle and team members are also encouraged to provide input on any modifications they would like to add to Elle. As critical nurses, we are excited that we will finally have a charting system that downloads our vital signs electronically. Before Elle, we had to write our vital signs every 15 minutes on each of our two patients. It might not seem like a big deal, but writing vital signs for two patients can take up a considerable amount of time, especially when a patient is unstable and on multiple drips. If nurses were not involved in the EHR design, downloading vital signs might be something that was overlooked again.
>Human Resource Management homework help
UncategorizedThe organization we are using is the “Department of Transportation.” I need at least two paragraphs for each bulleted question.
Organize your material in a logical sequence and support your plan using your textbook, peer-reviewed research, and other sources.
Format your assignment according to APA guidelines.
Information Systems homework help
UncategorizedDetails:
If you want to email me a question about your assignments I’m happy to troubleshoot remotely. However, if I need to look at your work, upload your assignment to Canvas. IU removes files from email attachments that contain macros/VBA or are zip archives. Also, Excel files with large datasets, pivot tables, Tables, images, and charts tend to get large, so Canvas is the best option.
Assignment:
The purpose of this application will be for analysis and visualization. While the design of your application and the majority of the analysis tools used will be up to you, there are a few minimum requirements your application must meet.
Requirements:
OR:
Include at least one example of a time intelligence function your analysis.
My grading criteria is as follows:
Summary of Deliverables:
For this assignment you should submit a single .pbix file and any associated files (Access Database, csv files, etc) to Canvas.
Submit all documents to Canvas before the posted due date.
EXPLAIN THE IMPORTANCE OF QUALITY ATTACHMENTS TO HEALTHY INFANT DEVELOPMENT
UncategorizedPlease respond to each questions. Each response should be concise and between 2–3 paragraphs in length. •Use MS Word to write your responses, and submit your answers to all three questions in one Word document. •Copy and paste each question within the document so that your Instructor can see to which question you are responding.
1.Based on what you have read in Chapters 1 & 2 of your course text, explain—using examples—how experiences supporting the following developmental areas contribute to healthy brain development: physical, emotional, social, cognitive/ language development.
2.Based on pages 68-74 of your course text, explain the importance of quality attachments to healthy infant development and identify at least three strategies caregivers can use to support secure attachments.
3.Observing and recording infant development can and should play a critical role in ensuring that developmentally appropriate practices are in place. Based on pages 124-134, identify and explain three kinds of observation methods that can and should be used to assess infant development and when each is likely to be employed.
>American history homework help
Uncategorized“If children do not understand the Constitution, they cannot understand how our government functions, or what their rights and responsibilities are as citizens of the United States.” – John Roberts
Although the Judiciary Act of 1789 established the legal concept of judicial review, it was the 1803 Supreme Court Case, Marbury v. Madison, which established the Supreme Court as the arbiter of whether the executive actions, congressional legislation, or lower court judicial decisions are constitutional.
In 1803, the Supreme Court heard the case, Marbury v. Madison. Chief Justice John Marshall, writing on behalf of a unanimous court, stated “it is emphatically the province and duty of the judicial department to say what the law is.” (Marbury v. Madison, 1803) In other words, the Supreme Court has the power to the final decider on what is constitutional or unconstitutional – be it congressional legislation, executive action, or judicial decisions. The Supreme Court’s power of judicial review is a salient component of this country’s ‘checks and balances’ system. Here is a full account of Marbury v. Madison from the U.S. Archives.
Today, the Supreme Court routinely hears cases that evaluate the constitutional authority of executive actions, congressional legislation, and lower court judicial decisions.
Directions: Using the required, academic readings, and supplemental academic research, please address the following while adhering to the Discussion Board Rubric:
Reference:
Marbury v. Madison (1803). (n.d.). Retrieved from https://www.ourdocuments.gov/doc.php?flash=true&doc=19.